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88345

Sigma-Aldrich

Thiomorpholine hydrochloride

≥98.0% (AT)

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About This Item

Empirical Formula (Hill Notation):
C4H9NS · HCl
CAS Number:
Molecular Weight:
139.65
Beilstein/REAXYS Number:
3908104
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥98.0% (AT)

form

crystals

mp

174-177 °C

functional group

thioether

storage temp.

2-8°C

SMILES string

Cl[H].C1CSCCN1

InChI

1S/C4H9NS.ClH/c1-3-6-4-2-5-1;/h5H,1-4H2;1H

InChI key

QSJAHJYXDRUZMY-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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J I Levin et al.
Bioorganic & medicinal chemistry letters, 16(6), 1605-1609 (2006-01-24)
A series of thiomorpholine sulfonamide hydroxamate TACE inhibitors, all bearing propargylic ether P1' groups, was explored. In particular, compound 5h has excellent in vitro potency against isolated TACE enzyme and in cells, oral activity in a model of TNF-alpha production
[Study of antiradiation drugs. I. Synthesis of some mercapto and amino derivatives of thiomorpholine (author's transl)].
F X Chen et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 15(8), 482-488 (1980-08-01)
Dominik Cincić et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 14(2), 747-753 (2007-10-24)
We demonstrate the supramolecular and structural equivalence of two halogen-bond donors (I and Br) and three acceptors (O, NH and S) through the synthesis of seven isostructural halogen-bonded cocrystals, involving six different molecules: 1,4-dibromo- and 1,4-diiodotetrafluorobenzene (donors) and thiomorpholine, thioxane
B Combourieu et al.
Biodegradation, 9(6), 433-442 (1999-05-21)
Spectrophotometric assays of Mycobacterium aurum MO1 cells extracts gave evidence of a soluble cytochrome P450, involved in the degradative pathway of morpholine, a waste product from the chemical industry. In order to get further information, the kinetics of the biodegradation
I T Ermakova et al.
Mikrobiologiia, 77(5), 617-622 (2008-11-14)
A screening of lignin-degrading basidial fungi that can grow in the presence of thiomorpholine derivatives (the mixture of 1,4-perhydrothiazines) has been performed. Strain Bjerkandera adusta VKM F-3477 was shown to have the maximal rate of growth in the presence of

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