726419

2-(Chloromethyl)naphthalene

≥97.0%

• Synonym(s): β-Naphthylmethyl chloride, 2-Menaphthyl chloride, 2-Naphthylmethyl chloride
• Empirical Formula (Hill Notation): C₁₁H₉Cl
• CAS Number: 2506-41-4
• Molecular Weight: 176.64
• Beilstein/REAXYS Number: 742185
• EC Number: 219-713-5
• MDL number: MFCD00046488
• UNSPSC Code: 12352100
• PubChem Substance ID: 329764234
• NACRES: NA.22

Properties

• assay: ≥97.0% (GC); ≥97.0%; 97.0-103.0% (T)
• form: crystals
• SMILES string: ClCc1ccc2ccccc2c1
• InChI: 1S/C11H9Cl/c12-8-9-5-6-10-3-1-2-4-11(10)7-9/h1-7H,8H2
• InChI key: MPCHQYWZAVTABQ-UHFFFAOYSA-N

Description

Application

• Improving insulin sensitivity: Research highlights dihydroberberine′s capacity to enhance insulin sensitivity through AMPK activation, offering a promising therapeutic strategy for managing insulin resistance and type 2 diabetes (Lewis and Falk, 2022).



• Anti-inflammatory effects: A study conducted on the anti-inflammatory properties of dihydroberberine found significant reductions in inflammatory markers, suggesting its potential as an anti-inflammatory agent in metabolic syndrome (Dian et al., 2022).



• Enhancing bioavailability: Investigations into the oral bioavailability of dihydroberberine demonstrate improvements over its precursor berberine, highlighting its superior pharmacokinetic profile which could lead to more effective clinical applications (Murakami, Bodor, and Bodor, 2023).



• Glucose uptake mechanisms: Studies on dihydroberberine have shown its effectiveness in facilitating glucose uptake, an essential function for metabolic health, through its interaction with cellular transport mechanisms (Moon et al., 2021).

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P305 + P351 + P338 - P310
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable