716243

1-Isopropyl-1H-pyrazole-4-boronic acid pinacol ester

97%

• Synonym(s): 1-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
• Empirical Formula (Hill Notation): C₁₂H₂₁BN₂O₂
• CAS Number: 879487-10-2
• Molecular Weight: 236.12
• MDL number: MFCD11867881
• UNSPSC Code: 12352103
• PubChem Substance ID: 329763373
• NACRES: NA.22

Properties

• assay: 97%
• form: solid
• mp: 36-44 °C
• storage temp.: 2-8°C
• SMILES string: CC(C)n1cc(cn1)B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C12H21BN2O2/c1-9(2)15-8-10(7-14-15)13-16-11(3,4)12(5,6)17-13/h7-9H,1-6H3
• InChI key: OGYYMVGDKVJYSU-UHFFFAOYSA-N

Description

Application

1-Isopropyl-1H-pyrazole-4-boronic acid pinacol ester can be used as a reactant to synthesize:

• Imidazo[1,2-a]pyrazine based phosphodiesterase 10A inhibitors.
• Pyrido[3,4-d]pyrimidin-4-(3H)-one based KDM4 and KDM5 (histone lysine demethylase families) inhibitors.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available