703540

2,2,6,6-Tetramethylpiperidinylmagnesium chloride lithium chloride complex solution

1.0 M in THF/toluene

• Synonym(s): TMPMgCl·LiCl
• Empirical Formula (Hill Notation): C₉H₁₈Cl₂LiMgN
• CAS Number: 898838-07-8
• Molecular Weight: 242.40
• MDL number: MFCD12546030
• UNSPSC Code: 12352103
• PubChem Substance ID: 329762048
• NACRES: NA.22

Properties

• form: liquid
• reaction suitability: reaction type: Grignard Reaction
• concentration: 1.0 M in THF/toluene; 20 % (w/w)
• density: 0.96 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: [Li+].[Cl-].CC1(C)CCCC(C)(C)N1[Mg]Cl
• InChI: 1S/C9H18N.2ClH.Li.Mg/c1-8(2)6-5-7-9(3,4)10-8;;;;/h5-7H2,1-4H3;2*1H;;/q-1;;;+1;+2/p-2
• InChI key: JHBZAAACZVPPRQ-UHFFFAOYSA-L

Description

Application

Selective Deprotonations using Knochel-Hauser-Base

2,2,6,6-Tetramethylpiperidinylmagnesium chloride lithium chloride complex is a non-nucleophilic Knochel-Hauser base mainly used for the magnesiation of functionalized arenes and heteroarenes to prepare the corresponding Grignard reagents. It can also be used as a base in the synthesis of Π-conjugated polymers via catalyst-transfer polycondensation.

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Product of Albemarle US Inc

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H314,H335,H336,H351,H361d
• pcodes: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014,EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: 5.0 °F
• flash_point_c: -15 °C