647241

(R)-(−)-1-Methyl-3-pyrrolidinol

97%

• Synonym(s): (3R)-1-Methylpyrrolidin-3-ol, (R)-(−)-3-Hydroxy-N-methylpyrrolidine, (R)-N-Methyl-3-pyrrolidinol
• Empirical Formula (Hill Notation): C₅H₁₁NO
• CAS Number: 104641-60-3
• Molecular Weight: 101.15
• MDL number: MFCD03788747
• UNSPSC Code: 12352005
• PubChem Substance ID: 24883519
• NACRES: NA.22

Properties

• assay: 97%
• optical activity: [α]20/D -7°, c = 1% in chloroform
• refractive index: n20/D 1.4640 (lit.)
• bp: 50-52 °C/1 mmHg (lit.)
• density: 0.921 g/mL at 25 °C (lit.)
• SMILES string: CN1CC[C@@H](O)C1
• InChI: 1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m1/s1
• InChI key: FLVFPAIGVBQGET-RXMQYKEDSA-N

Description

Application

Reactant for:

• Asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors
• Preparation of diaryl acylaminopyrimidines as adenosine A2A antagonists
• Synthesis of analogs of istaroxime, a potent inhibitor of Na⁺,K⁺-ATPase
• Synthesis of pharmacologically active stereoisomers of N-substituted soft anticholinergics

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 158.0 °F
• flash_point_c: 70 °C
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter