549223

3,4-Difluorothiophenol

96%

• Linear Formula: F₂C₆H₃SH
• CAS Number: 60811-24-7
• Molecular Weight: 146.16
• MDL number: MFCD03094279
• UNSPSC Code: 12352100
• PubChem Substance ID: 24879070
• NACRES: NA.22

Properties

• assay: 96%
• refractive index: n20/D 1.528 (lit.)
• bp: 169-170 °C (lit.)
• density: 1.323 g/mL at 25 °C (lit.)
• SMILES string: Fc1ccc(S)cc1F
• InChI: 1S/C6H4F2S/c7-5-2-1-4(9)3-6(5)8/h1-3,9H
• InChI key: BGVRHDQMTMPAEZ-UHFFFAOYSA-N

Description

General description

3,4-Difluorothiophenol is a halo-substituted thiol derivative.

application

3,4-Difluorothiophenol may be used:

• To prepare a novel 3,4-difluorophenylthiomethyl group containing phthalazine derivative, which shows high cytotoxic activity.
• To prepare a fluorothiophenyl modified poly(vinyl chloride) membrane with improved gas permeability efficiency.
• As a ligand to synthesize noble metal quantum clusters (QCs).
• To prepare ethyl 5-(aminosulfonyl)-2-[(3,4-difluorophenyl)thio]nicotinate, an intermediate for preparing potent thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H315,H319,H335
• pcodes: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 120.0 °F - closed cup
• flash_point_c: 48.9 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter