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52270

Sigma-Aldrich

1-Hexadecanethiol

≥95.0% (GC)

Synonym(s):

Cetyl mercaptan, Hexadecyl mercaptan, Mercaptan C16

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100 ML
$156.00
500 ML
$241.00

About This Item

Linear Formula:
CH3(CH2)15SH
CAS Number:
Molecular Weight:
258.51
Beilstein/REAXYS Number:
1748495
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$156.00


Available to ship onApril 15, 2025Details


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assay

≥95.0% (GC)

refractive index

n20/D 1.462 (lit.)
n20/D 1.464

bp

184-191 °C/7 mmHg (lit.)

mp

18-20 °C (lit.)

transition temp

solidification point 15-18 °C(lit.)

density

0.84 g/mL at 25 °C (lit.)

functional group

thiol

SMILES string

CCCCCCCCCCCCCCCCS

InChI

1S/C16H34S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3

InChI key

ORTRWBYBJVGVQC-UHFFFAOYSA-N

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General description

1-Hexadecanethiol (HDT) readily forms self-assembled monolayer (SAMs) on gold surfaces.[1] Phase separation characteristics of binary SAMs [made up of HDT and 3-mercaptopropionic acid] on the surface of Au(111) have been investigated.[2] Interaction between gold surface and SAM of HDT has been investigated by atomic force microscopy (AFM).[3]

Application

1-Hexadecanethiol has been used in the preparation of cholesterol-PIE12-trimer and alkyl-PIE12-trimer (PIE12-trimer = protease-resistant trimeric D-peptide inhibitor).[4] It may be used for the functionalization of silver nanowires.[5]

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

215.6 °F - closed cup

flash_point_c

102 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Mohammad R Shadnam et al.
Langmuir : the ACS journal of surfaces and colloids, 20(7), 2667-2676 (2005-04-20)
The development of a methodology to manipulate surface properties of a self-assembled monolayer (SAM) of alkanethiol on a gold film using direct laser patterning is the objective of this paper. The present study demonstrates proof of the concept for the
S Neupane et al.
Langmuir : the ACS journal of surfaces and colloids, 34(1), 66-72 (2017-12-10)
Controlling the molecular organization of organic self-assembled monolayers (SAM) is of utmost importance in nanotechnology, molecular electronics, and surface science. Here we propose two well-differentiated approaches, double printing based on microcontact printing (μ-cp) and molecular backfilling adsorption, to produce complex
Stable colloidal solutions of high-temperature-annealed L10 FePt nanoparticles.
Anastasia Delattre et al.
Small (Weinheim an der Bergstrasse, Germany), 6(8), 932-936 (2010-03-10)
Combining surface chemistry with a FRET-based biosensor to study the dynamics of RhoA GTPase activation in cells on patterned substrates.
Louis Hodgson et al.
Journal of the American Chemical Society, 129(30), 9264-9265 (2007-07-13)
M N Yousaf et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(11), 5992-5996 (2001-05-17)
This report describes the development of an electroactive mask that permits the patterning of two different cell populations to a single substrate. This mask is based on a self-assembled monolayer of alkanethiolates on gold that could be switched from a

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