497312
4-Piperidinemethanol
97%
Synonym(s):
4-(Hydroxymethyl)piperidine
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5 G
$203.00
25 G
$995.00
About This Item
Empirical Formula (Hill Notation):
C6H13NO
CAS Number:
Molecular Weight:
115.17
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
97%
bp
118-120 °C/10 mmHg (lit.)
mp
55-59 °C (lit.)
functional group
hydroxyl
SMILES string
OCC1CCNCC1
InChI
1S/C6H13NO/c8-5-6-1-3-7-4-2-6/h6-8H,1-5H2
InChI key
XBXHCBLBYQEYTI-UHFFFAOYSA-N
Related Categories
General description
4-Piperidinemethanol is a cyclic secondary amine. Its standard molar enthalpies of combustion, sublimation and formation have been determined.[1]
Application
4-Piperidinemethanol may be used in the preparation of:
- N-tert-butoxycarbonyl-4-hydroxymethyl piperidine[2]
- desferrioxamine B (DFO) containing third generation triazine dendrimer[3]
- ethyl 3-(4-(hydroxymethyl)piperidin-1-yl)propanoate (EHMPP)[4]
- 4-(hydroxymethyl)piperidine-1-carbodithioic acid (HL)[5]
- 1-[[(1E)-2-(4-chlorophenyl)ethenyl]sulfonyl]-4-piperidinemethanol[6]
Substrate used in solid-phase organic synthesis of a secondary amine.[7]
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk_germany
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Enzymatic synthesis, thermal and crystalline properties of a poly (β-amino ester) and poly (lactone-co-β-amino ester) copolymers.
Martino L, et al.
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Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitor.
Nishida H, et al.
Chemical & Pharmaceutical Bulletin, 49(10), 1237-1244 (2001)
Jongdoo Lim et al.
Bioorganic & medicinal chemistry, 18(15), 5749-5753 (2010-07-10)
The synthesis of a third generation triazine dendrimer, 1, containing multiple, iron-sequestering desferrioxamine B (DFO) groups is described. Benzoylation of the hydroxamic acid groups of DFO and formation of a reactive dichlorotriazine provide the intermediate for reaction with the second
Christian A Olsen et al.
Organic letters, 6(12), 1935-1938 (2004-06-05)
[reaction: see text] An expedient solid-phase synthetic approach to secondary and tertiary amines was developed. The protocol employs conversion of resin-bound amino alcohols to the corresponding iodides, followed by iodide displacement with primary or secondary amines or with unprotected amino
Synthesis, spectroscopy, and biological activity of heterobimetallic complexes containing Sn (IV) and Pd (II) with 4-(hydroxymethyl) piperidine-1-carbodithioic acid.
Anwar MT, et al.
Russ. J. Gen. Chem., 83(12), 2380-2385 (2013)
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