440655

Boc-Asp(OBzl)-OH

98%

• Synonym(s): N-(tert-Butoxycarbonyl)-L-aspartic acid 4-benzyl ester, Boc-L-aspartic acid 4-benzyl ester
• Linear Formula: C₆H₅CH₂OCOCH₂CH(COOH)NHCOOC(CH₃)₃
• CAS Number: 7536-58-5
• Molecular Weight: 323.34
• Beilstein/REAXYS Number: 2064127
• EC Number: 231-406-8
• MDL number: MFCD00065564
• UNSPSC Code: 12352200
• PubChem Substance ID: 24867616

Properties

• assay: 98%
• optical activity: [α]20/D −19.5°, c = 2 in DMF
• mp: 98-102 °C (lit.)
• SMILES string: [H][C@@](CC(=O)OCc1ccccc1)(NC(=O)OC(C)(C)C)C(O)=O
• InChI: 1S/C16H21NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-13(18)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1
• Inchi Key: SOHLZANWVLCPHK-LBPRGKRZSA-N

Description

Application

Starting material for the enantiospecific synthesis of (R)-(+)-Boc-iturinic acid (n-C₁₄), the L-aspartic series of thrombin inhibitors, and diketopiperazine tetrapeptides. Used in the preparation of a novel tricyclic dipeptide mimetic based on a [6H]-azepino indoline nucleus.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)