428531

5-(4-Chlorophenyl)-2-furoic acid

97%

• Synonym(s): 5-(4-Chlorophenyl)-2-furancarboxylic acid
• Empirical Formula (Hill Notation): C₁₁H₇ClO₃
• CAS Number: 41019-45-8
• Molecular Weight: 222.62
• MDL number: MFCD00216587
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866497
• NACRES: NA.22

Properties

• assay: 97%
• mp: 198-201 °C (dec.) (lit.)
• SMILES string: OC(=O)c1ccc(o1)-c2ccc(Cl)cc2
• InChI: 1S/C11H7ClO3/c12-8-3-1-7(2-4-8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)
• InChI key: XIPQHWUSDHTXOO-UHFFFAOYSA-N

Description

General description

5-(4-Chlorophenyl)-2-furoic acid (5-(4-chlorophenyl)-2-furancarboxylic acid) is a 5-aryl-2-furancarboxylic acid. It has been synthesized by oxidation of the corresponding furaldehyde with silver nitrate and sodium hydroxide. It serves as an intermediate for the synthesis of 5-(5-aryl-2-furyl)-tetrazol-1-ylacetic acids, which are employed in the synthesis of semisynthetic cephalosporines.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves