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369527

Sigma-Aldrich

N,N-Dimethylbutylamine

99%

Synonym(s):

N-Butyldimethylamine

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About This Item

Linear Formula:
CH3(CH2)3N(CH3)2
CAS Number:
927-62-8
Molecular Weight:
101.19
Beilstein/REAXYS Number:
1731308
EC Number:
213-156-1
MDL number:
MFCD00043838
UNSPSC Code:
12352100
PubChem Substance ID:
24862984

assay

99%

refractive index

n20/D 1.398 (lit.)

bp

93.3 °C/750 mmHg (lit.)

density

0.721 g/mL at 25 °C (lit.)

SMILES string

CCCCN(C)C

InChI

1S/C6H15N/c1-4-5-6-7(2)3/h4-6H2,1-3H3

InChI key

DJEQZVQFEPKLOY-UHFFFAOYSA-N

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General description

N,N-Dimethylbutylamine is a tertiaryalkylamine. X-ray photoelectron spectra (XPS) of Si(001) surfaces exposed to N,N-dimethylbutylamine at 300K has been reported.

application

N,N-Dimethylbutylamine is suitable for use in the fabrication of polystyrene-based nano-LC monolithic columns for the separation of protein molecules. It may be used as ion-pairing reagent in a study involving comparison of performance of six ion-pairing reagents as mobile phase modifiers for oligonucleotide LC/MS.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

23.0 °F - closed cup

flash_point_c

-5 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Leta Deressa Tolesa et al.
International journal of biological macromolecules, 130, 818-826 (2019-03-07)
Ammonium-based ionic liquids (ILs): diisopropylethylammonium acetate ([DIPEA][Ac]), diisopropylethylammonium propanoate ([DIPEA][P]) and dimethylbutylammonium acetate ([DMBA][Ac]) are used for the extraction of chitin from shrimp shells. The extracted chitins were characterized by FT-IR, TGA, XRD, SEM and 1H NMR. The yield of
Lingzhi Gong et al.
Rapid communications in mass spectrometry : RCM, 28(4), 339-350 (2014-01-08)
A sensitive and selective liquid chromatography/mass spectrometry (LC/MS) method is essential for quality control of synthetic oligonucleotides. However, researchers are still searching for improvements to ion-pairing reagents for ion-pairing reversed-phase LC/MS. This study performed a comprehensive comparison of six ion-pairing
Anna Kilanowska et al.
Analytical and bioanalytical chemistry, 412(27), 7453-7467 (2020-08-29)
The aim of the present investigation was the analysis and identification of antisense oligonucleotide metabolism products after incubation with human liver microsomes regarding four different oligonucleotide modifications. Separation and detection methods based on the use of liquid chromatography coupled with
Łukasz Nuckowski et al.
The Analyst, 144(15), 4622-4632 (2019-06-28)
Our research focused on applying microextraction by packed sorbent to extracting antisense oligonucleotides from serum samples. The tested sorbents included poly(styrene-co-divinylbenzene), octyl, octadecyl, and unmodified silica gel. As nonpolar sorbents were used for highly-polar molecules, this required ion-pair mode. Comprehensive
Sylwia Studzińska et al.
Analytical and bioanalytical chemistry, 408(6), 1585-1595 (2016-01-14)
Ultra high performance liquid chromatography hyphenated with quadrupole time-of-flight mass spectrometry was used to determine the products of the in vitro metabolism of phosphorothioate oligonucleotides. These compounds may be used during antisense therapy as synthetic fragments of genes. For this
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