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368520

Sigma-Aldrich

Tris(2-benzimidazolylmethyl)amine

technical grade, 92%

Synonym(s):

(BimH)3, N,N-Bis(1H-benzimidazol-2-ylmethyl)-1H-benzimidazole-2-methanamine

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About This Item

Empirical Formula (Hill Notation):
C24H21N7
CAS Number:
Molecular Weight:
407.47
MDL number:
UNSPSC Code:
12352300

grade

technical grade

assay

92%

mp

277-281 °C (lit.)

SMILES string

C(N(Cc1nc2ccccc2[nH]1)Cc3nc4ccccc4[nH]3)c5nc6ccccc6[nH]5

InChI

1S/C24H21N7/c1-2-8-17-16(7-1)25-22(26-17)13-31(14-23-27-18-9-3-4-10-19(18)28-23)15-24-29-20-11-5-6-12-21(20)30-24/h1-12H,13-15H2,(H,25,26)(H,27,28)(H,29,30)

InChI key

YQIGEJHOYBUSLR-UHFFFAOYSA-N

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Application

Reactant for synthesis of:
  • Carbonic anhydrase models
  • Porous lanthanide tris(benzimidazolylmethyl)amine nitrato frameworks

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Certificates of Analysis (COA)

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Francisco-Javier Gamo et al.
Nature, 465(7296), 305-310 (2010-05-21)
Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug resistance is widespread, no new chemical class of antimalarials has been introduced into clinical practice since 1996 and there is a recent rise of parasite strains with
David Plouffe et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(26), 9059-9064 (2008-06-27)
The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-throughput cell-based screen (1,536-well format) based on proliferation of Plasmodium falciparum (Pf) in

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