Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

366625

Sigma-Aldrich

5-Fluoro-2-methylbenzoic acid

99%

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
FC6H3(CH3)CO2H
CAS Number:
33184-16-6
Molecular Weight:
154.14
MDL number:
MFCD00042294
UNSPSC Code:
12352100
PubChem Substance ID:
24862679

assay

99%

mp

130-132 °C (lit.)

functional group

carboxylic acid
fluoro

SMILES string

Cc1ccc(F)cc1C(O)=O

InChI

1S/C8H7FO2/c1-5-2-3-6(9)4-7(5)8(10)11/h2-4H,1H3,(H,10,11)

InChI key

JVBLXLBINTYFPR-UHFFFAOYSA-N

Application

5-Fluoro-2-methylbenzoic acid may be used in the preparation of:
  • 5-fluoro-3-hydroxy-2-methylbenzoic acid[1]
  • 5-fluoro-2-methyl-3-nitrobenzoic acid methyl ester[2]
  • 5-fluoro-N,2-dimethylbenzamide[3]

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBC2088V
MKBC2088
03301TD
U17502
13803TA

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

E Takashiro et al.
Bioorganic & medicinal chemistry, 7(9), 2063-2072 (1999-10-26)
The structure-activity relationship of HIV-1 protease (HIV-1 PR) inhibitors containing alpha-hydroxy-beta-amino acids is discussed. We demonstrated that substituent groups on the P1 aromatic rings of the inhibitors exert significant influence on their biological activity. Inhibitors bearing an alkyl or a
Multkilogram Scale-Up of a Reductive Alkylation Route to a Novel PARP Inhibitor.
Gillmore AT, et al.
Organic Process Research & Development, 16(12), 2063-2072 (1999)
Xing Fan et al.
Bioorganic & medicinal chemistry, 19(16), 4935-4952 (2011-07-23)
HIV-1 integrase (IN) is a validated therapeutic target for antiviral drug design. However, the emergence of viral strains resistant to clinically studied IN inhibitors demands the discovery of novel inhibitors that are structurally as well mechanistically different. Herein, we describe

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service