346160

Ethynylmagnesium chloride solution

0.5 M in THF

• Synonym(s): Chloromagnesium acetylide
• Linear Formula: CH≡CMgCl
• CAS Number: 65032-27-1
• Molecular Weight: 84.79
• MDL number: MFCD00075343
• UNSPSC Code: 12352103
• PubChem Substance ID: 24861377
• NACRES: NA.22

Properties

• form: liquid
• reaction suitability: reaction type: Grignard Reaction
• concentration: 0.5 M in THF
• density: 0.921 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: Cl[Mg]C#C
• InChI: 1S/C2H.ClH.Mg/c1-2;;/h1H;1H;/q;;+1/p-1
• InChI key: YEWNLGTVYUADOR-UHFFFAOYSA-M

Description

Application

Ethynylmagnesium chloride solution can be used:

• To synthesize 1-ethynyldeoxyribose derivatives which can further undergo Sonogashira coupling with various aryl, heteroaryl, and metallocenyl derivatives.
• In one of the key synthetic steps of substituted naphthostyrils.
• In the preparation of propargylic ester precursor for the synthesis of 1,3-dienylphosphonates.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H335,H336,H351
• pcodes: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: -16.6 °F - closed cup
• flash_point_c: -27 °C - closed cup