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327859

Sigma-Aldrich

2′,3′-Dideoxy-5-iodouridine

97%

Synonym(s):

5-Iodo-2′,3′-dideoxyuridine

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About This Item

Empirical Formula (Hill Notation):
C9H11IN2O4
CAS Number:
105784-83-6
Molecular Weight:
338.10
Beilstein/REAXYS Number:
5956836
MDL number:
MFCD00074877
UNSPSC Code:
12352100
PubChem Substance ID:
24859698
NACRES:
NA.22

assay

97%

mp

176 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

OC[C@@H]1CC[C@@H](O1)N2C=C(I)C(=O)NC2=O

InChI

1S/C9H11IN2O4/c10-6-3-12(9(15)11-8(6)14)7-2-1-5(4-13)16-7/h3,5,7,13H,1-2,4H2,(H,11,14,15)/t5-,7+/m0/s1

InChI key

OBGFSDPYSQAECJ-CAHLUQPWSA-N

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General description

2′,3′-Dideoxy-5-iodouridine is commonly used as research tool for antiviral and anticancer studies.

Application

2′,3′-Dideoxy-5-iodouridine (5-Iodo-2′,3′-dideoxyuridine) was used in preparation of fluorescence-tagged chain-terminating reagents, T-526, for rapid DNA sequencing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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J M Prober et al.
Science (New York, N.Y.), 238(4825), 336-341 (1987-10-16)
A DNA sequencing system based on the use of a novel set of four chain-terminating dideoxynucleotides, each carrying a different chemically tuned succinylfluorescein dye distinguished by its fluorescent emission is described. Avian myeloblastosis virus reverse transcriptase is used in a
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Aldrichimica Acta, 20, 52-52 (1987)

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