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Sigma-Aldrich

Hexaethylene glycol

97%, average MN 300

Synonym(s):

Polyethylene glycol, 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol

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About This Item

Linear Formula:
H(OCH2CH2)6OH
CAS Number:
Molecular Weight:
282.33
Beilstein/REAXYS Number:
1638281
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

product name

Hexaethylene glycol, 97%

Quality Level

assay

97%

form

liquid

mol wt

average Mn 300

refractive index

n20/D 1.465 (lit.)

bp

217 °C/4 mmHg (lit.)

mp

5-7 °C (lit.)

density

1.127 g/mL at 25 °C (lit.)

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

OCCOCCOCCOCCOCCOCCO

InChI

1S/C12H26O7/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h13-14H,1-12H2

InChI key

IIRDTKBZINWQAW-UHFFFAOYSA-N

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Application

Substrate employed in the synthesis of binaphthol-based macrocyclic ethers using intramolecular oxidative coupling with CuCl(OH)-TMEDA.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

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Tetrahedron Letters, 47, 8563-8563 (2006)
Dorota Bartczak et al.
Nanoscale, 4(15), 4470-4472 (2012-06-30)
We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some
Paul A Bertin et al.
Journal of the American Chemical Society, 128(13), 4168-4169 (2006-03-30)
We present a rational approach for assembling diverse bioactive agents, such as DNA, proteins, and drug molecules, into core-shell multifunctional polymeric nanoparticles (PNPs) that can be internalized in human breast cancer cells. Using ring-opening metathesis polymerization (ROMP), block copolymers containing
Ewelina Burakowska et al.
Small (Weinheim an der Bergstrasse, Germany), 5(19), 2199-2204 (2009-07-03)
A convenient methodology for the synthesis of photolabile crosslinked hyperbranched polyglycerol nanocapsules is presented. These nanocarriers selectively and efficiently bind ionic guest molecules. The stability of the host-guest complexes formed depends on the counterion of the guest molecules. Moreover, the
Xin Li et al.
Analytical chemistry, 84(6), 2609-2613 (2012-03-03)
Lipophilicity of chemicals and drug candidates is normally described in terms of octanol/water partitioning and log P. We investigated an alternate approach to lipophilicity determination using a mimic of an alkyl alcohol with compound partitioning quantified using acoustic sensing. A

Articles

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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