225908

Allylmagnesium chloride solution

2.0 M in THF

• Synonym(s): Allyl magnesium chloride, Allylchloromagnesium, Allylmagnesium chloride, Chloro-2-propen-1-ylmagnesium
• Linear Formula: CH₂=CHCH₂MgCl
• CAS Number: 2622-05-1
• Molecular Weight: 100.83
• Beilstein/REAXYS Number: 3587316
• MDL number: MFCD00000473
• UNSPSC Code: 12352103
• PubChem Substance ID: 24853531
• NACRES: NA.22

Properties

• Quality Level: 100
• reaction suitability: reaction type: Grignard Reaction
• concentration: 2.0 M in THF
• density: 0.995 g/mL at 25 °C
• SMILES string: Cl[Mg]CC=C
• InChI: 1S/C3H5.ClH.Mg/c1-3-2;;/h3H,1-2H2;1H;/q;;+1/p-1
• InChI key: PLYLAFITHJUEGX-UHFFFAOYSA-M

Description

General description

Allylmagnesiumchloride solution is an organic compound commonly used as a Grignard reagent inchemical reactions. It is used for the allylation of carbonyl compounds, such as aldehydes and ketones.

Application

Allylmagnesium chloride solution is used as a Grignard reagent in the preparation of:

• Antipsychotic clopixol.
• Polysilane–crown ether polymer (PSEC) using hexachloroplatinic acid as a catalyst.
• 1,7-disubstituted-1,2,3,4-tetrahydroisoquinolinesfrom 3,4-dihydroisoquinoline.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H260,H314,H335,H336,H351
• pcodes: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH014,EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 1
• flash_point_f: 1.4 °F - closed cup - Solvent
• flash_point_c: -17 °C - closed cup - Solvent
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter