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218448

Sigma-Aldrich

4-Nitroquinoline N-oxide

98%

Synonym(s):

4-NQO, 4-Nitroquinoline 1-oxide

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About This Item

Empirical Formula (Hill Notation):
C9H6N2O3
CAS Number:
56-57-5
Molecular Weight:
190.16
Beilstein/REAXYS Number:
165756
EC Number:
200-281-1
MDL number:
MFCD00006738
UNSPSC Code:
12352200

assay

98%

mp

154-156 °C (lit.)

SMILES string

[O-][N+](=O)c1cc[n+]([O-])c2ccccc12

InChI

1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H

InChI key

YHQDZJICGQWFHK-UHFFFAOYSA-N

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Product No.
Description
Pricing

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H350

Hazard Classifications

Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
18728BN
18011TS
16103BI
10425HO
08225CF

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J Peter Svensson et al.
PloS one, 7(5), e37368-e37368 (2012-05-23)
Studies in Saccharomyces cerevisiae show that many proteins influence cellular survival upon exposure to DNA damaging agents. We hypothesized that human orthologs of these S. cerevisiae proteins would also be required for cellular survival after treatment with DNA damaging agents.
Kwame Osei-Sarfo et al.
Carcinogenesis, 34(11), 2673-2681 (2013-06-21)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer affecting humans worldwide. To determine the potential mechanisms by which chronic tobacco and alcohol abuse lead to HNSCC of the oral cavity, we have used
Jing Li et al.
Oral oncology, 49(4), 299-305 (2012-11-29)
Lymph node metastasis is one of the most important prognostic factors in oral squamous cell carcinoma. However, regional lymph node metastasis from oral cancer has barely been investigated in 4-nitroquinoline-1-oxide (4NQO) models. In this study, we developed a 4NQO-treated mouse
Leon F Stankowski et al.
Environmental and molecular mutagenesis, 52(9), 738-747 (2011-10-25)
As part of the Stage III Pig-a multilaboratory validation trial, we examined the induction of CD59-negative reticulocytes and total red blood cells (RET(CD59-) and RBC(CD59-) , respectively) in male Sprague Dawley(®) rats treated with 4-nitroquinoline-1-oxide (4NQO), for 28 consecutive days
Francesca Trotta et al.
International journal of food microbiology, 153(3), 275-280 (2011-12-20)
Yeasts isolated from Italian beverages and foods (wine and cheeses) were identified as Saccharomyces cerevisiae and Debaryomyces hansenii by sequencing the D1/D2 domain of the 26S rRNA gene and differentiated, at strain level, by microsatellite PCR fingerprinting and RAPD-PCR. All
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