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186686

Sigma-Aldrich

7-(Trifluoromethyl)quinoline-4-thiol

95%

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About This Item

Empirical Formula (Hill Notation):
C10H6F3NS
CAS Number:
64415-07-2
Molecular Weight:
229.22
EC Number:
264-875-2
MDL number:
MFCD00006780
UNSPSC Code:
12352100
PubChem Substance ID:
24851235
NACRES:
NA.22

assay

95%

form

chunks

mp

222-225 °C (lit.)

SMILES string

FC(F)(F)c1ccc2c(S)ccnc2c1

InChI

1S/C10H6F3NS/c11-10(12,13)6-1-2-7-8(5-6)14-4-3-9(7)15/h1-5H,(H,14,15)

InChI key

DBWDEWRMEKXOFI-UHFFFAOYSA-N

Application

7-(Trifluoromethyl)quinoline-4-thiol was used to investigate the mechanism of generation of lipid-poor particles from high-density lipoprotein induced by cholesteryl ester transfer protein.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Cyrille Maugeais et al.
Biochimica et biophysica acta, 1831(11), 1644-1650 (2013-07-23)
Cholesteryl ester transfer protein (CETP), a key regulator of high-density lipoprotein (HDL) metabolism, induces HDL remodeling by transferring lipids between apolipoprotein B-containing lipoproteins and HDL, and/or by promoting lipid transfer between HDL subparticles. In this study, we investigated the mechanism

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