163759
PIPES
Synonym(s):
1,4-Piperazinediethanesulfonic acid, Piperazine-1,4-bis(2-ethanesulfonic acid), Piperazine-N,N′-bis(2-ethanesulfonic acid)
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About This Item
Empirical Formula (Hill Notation):
C8H18N2O6S2
CAS Number:
Molecular Weight:
302.37
Beilstein/REAXYS Number:
817713
EC Number:
MDL number:
UNSPSC Code:
12161700
Recommended Products
useful pH range
6.1-7.5
pKa (25 °C)
6.8
mp
>300 °C (lit.)
SMILES string
OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
InChI
1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
InChI key
IHPYMWDTONKSCO-UHFFFAOYSA-N
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D W MacGlashan et al.
The Journal of clinical investigation, 70(4), 747-751 (1982-10-01)
Although mediator release from mast cells and basophils plays a central role in the pathogenesis of human allergic disease, biochemical studies have been restricted to rat peritoneal mast cells and basophilic leukemia cells because they could be easily purified. We
K Hartmann et al.
Blood, 89(8), 2863-2870 (1997-04-15)
The factors that control migration of mast cells to sites of inflammation and tissue repair remain largely undefined. Whereas several recent studies have described chemotactic factors that induce migration of murine mast cells, only stem cell factor (SCF) is known
P S Baur et al.
Journal of microscopy, 109(3), 315-327 (1977-04-01)
PIPES, an organic based buffer, was used in the preparation of a variety of marine and mammalian tissues for electron microscopic study. The ultrastructural results demonstrate that this buffer renders superior ultrastructural details to those obtained with some of the
D Kristofferson et al.
The Journal of cell biology, 102(3), 1007-1019 (1986-03-01)
Different types of unusual dynamic behavior have been reported for steady-state microtubules. While almost all earlier reports relied on kinetic measurements of bulk polymerization, we have directly visualized the steady-state addition of subunits to individual microtubules through the use of
R W Holz et al.
Journal of neurochemistry, 46(6), 1835-1842 (1986-06-01)
Hyperosmotic solutions inhibit exocytosis of catecholamine from adrenal chromaffin cells at a step after Ca2+ entry into the cells. The possibility that the inhibition resulted from an inability of shrunken secretory granules to undergo exocytosis was investigated in cells with
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