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Sigma-Aldrich

HEPES

Synonym(s):

4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

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About This Item

UNSPSC Code:
12352200

form

chunks

solubility

water: 0.5 g/mL, clear, colorless

Application

Buffer useful in the physiological pH range.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Journal of Organic Chemistry, 58, 2663-2663 (1993)
Aldrichimica Acta, 16, 35-35 (1983)
M Vasseur et al.
The American journal of physiology, 264(1 Pt 1), C27-C31 (1993-01-01)
The fluorescence intensity of 6-methoxy-N-(3-sulfopropyl)quinolinium (SPQ) in an N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES) 2-(N-morpholino)ethanesulfonic acid (MES)-Tris(hydroxymethyl)aminomethane buffer, pH 7.0, decreased as a function of Cl- concentration and/or gluconate concentration, as expected. Contrary to expectation, however, the fluorescence intensity progressively increased as the
Sunbae Lee et al.
PloS one, 6(4), e18594-e18594 (2011-04-16)
The mechanisms by which MAP kinases recognize and phosphorylate substrates are not completely understood. Efforts to understand the mechanisms have been compromised by the lack of MAPK-substrate structures. While MAPK-substrate docking is well established as a viable mechanism for bringing
Min Soo Kim et al.
Nutrition research and practice, 5(3), 219-223 (2011-07-23)
Obesity has been reported to be associated with low grade inflammatory status. In this study, we investigated the inflammatory response as well as associated signaling molecules in immune cells from diet-induced obese mice. Four-week-old C57BL mice were fed diets containing

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