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Sigma-Aldrich

Trifluoroacetamide

97%

Synonym(s):

2,2,2-Trifluoroacetamide

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About This Item

Linear Formula:
CF3CONH2
CAS Number:
354-38-1
Molecular Weight:
113.04
Beilstein/REAXYS Number:
1753625
EC Number:
206-559-9
MDL number:
MFCD00008008
UNSPSC Code:
12352100
PubChem Substance ID:
24848677
NACRES:
NA.22

assay

97%

form

solid

bp

162.5 °C (lit.)

mp

65-70 °C (lit.)

SMILES string

NC(=O)C(F)(F)F

InChI

1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)

InChI key

NRKYWOKHZRQRJR-UHFFFAOYSA-N

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General description

Trifluoroacetamide is a good quencher of tryptophan fluorescence.

Application

Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
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