Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

10926

Sigma-Aldrich

9-Fluorenylmethyl N-hydroxycarbamate

≥99.0%

Synonym(s):

N-(9-Fluorenylmethoxycarbonyl)hydroxylamine, N-Fmoc-hydroxylamine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C15H13NO3
CAS Number:
Molecular Weight:
255.27
Beilstein/REAXYS Number:
7712144
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:

assay

≥99.0%

mp

164.5 °C (lit.)

application(s)

peptide synthesis

SMILES string

ONC(=O)OCC1c2ccccc2-c3ccccc13

InChI

1S/C15H13NO3/c17-15(16-18)19-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14,18H,9H2,(H,16,17)

InChI key

HHNJBGORPSTJDX-UHFFFAOYSA-N

Application

9-Fluorenylmethyl N-hydroxycarbamate (Fmoc-NHOH) can be used as a reactant to prepare:
  • N-Fmoc-aminooxy-2-chlorotrityl polystyrene, a solid-phase resin used to produce hydroxamic acids and peptidyl hydroxamic acids.[1]
  • 9-Fluorenylmethyl nosyloxycarbamate (Fmoc-NHONs) by reacting with nosyl chloride.[2]

Other Notes

Building block for the solid-phase synthesis of (peptide) hydroxamic acids on chlorotrityl resin[3]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of N-protected cyano aziridines
Fioravanti S, et al.
Synlett, 2004(06), 1083-1085 (2004)
S.L. Mellor et al.
Tetrahedron Letters, 38, 3311-3311 (1997)
N-Fmoc-aminooxy-2-chlorotrityl polystyrene resin: A facile solid-phase methodology for the synthesis of hydroxamic acids
Mellor SL, et al.
Tetrahedron Letters, 38(18), 3311-3314 (1997)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service