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105538

Sigma-Aldrich

7-Chloro-4-hydroxyquinoline

99%

Synonym(s):

7-Chloro-4-quinolinol

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About This Item

Empirical Formula (Hill Notation):
C9H6ClNO
CAS Number:
Molecular Weight:
179.60
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

99%

mp

276-279 °C (lit.)

SMILES string

Oc1ccnc2cc(Cl)ccc12

General description

7-Chloro-4-hydroxyquinoline is formed by the reaction of 4,7-dichloroquinoline with glacial acetic acid in anhydrous medium.

Biochem/physiol Actions

7-Chloro-4-hydroxyquinoline is an antitumor drug.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Customers Also Viewed

The reaction of 4, 7-dichloroquinoline with acetic acid.
Cutler RA and Surrey AR.
Journal of the American Chemical Society, 72(8), 3394-3395 (1950)
Antioxidative or prooxidative effect of 4-hydroxyquinoline derivatives on free-radical-initiated hemolysis of erythrocytes is due to its distributive status.
Liu ZQ, et al.
Biochim. Biophys. Acta Gen. Subj., 1570(2), 97-103 (2002)
Chloroquine metabolism in man: urinary excretion of 7-chloro-4-hydroxyquinoline and 7-chloro-4-aminoquinoline metabolites.
N D Brown et al.
Journal of chromatography, 345(1), 209-214 (1985-11-29)

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