105538
7-Chloro-4-hydroxyquinoline
99%
Synonym(s):
7-Chloro-4-quinolinol
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About This Item
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assay
99%
mp
276-279 °C (lit.)
SMILES string
Oc1ccnc2cc(Cl)ccc12
General description
7-Chloro-4-hydroxyquinoline is formed by the reaction of 4,7-dichloroquinoline with glacial acetic acid in anhydrous medium.
Biochem/physiol Actions
7-Chloro-4-hydroxyquinoline is an antitumor drug.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The reaction of 4, 7-dichloroquinoline with acetic acid.
Journal of the American Chemical Society, 72(8), 3394-3395 (1950)
Antioxidative or prooxidative effect of 4-hydroxyquinoline derivatives on free-radical-initiated hemolysis of erythrocytes is due to its distributive status.
Biochim. Biophys. Acta Gen. Subj., 1570(2), 97-103 (2002)
Chloroquine metabolism in man: urinary excretion of 7-chloro-4-hydroxyquinoline and 7-chloro-4-aminoquinoline metabolites.
Journal of chromatography, 345(1), 209-214 (1985-11-29)
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