T0557

Sodium taurodeoxycholate hydrate

BioXtra, ≥97% (TLC)

• Synonym(s): 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
• Linear Formula: C₂₆H₄₄NO₆SNa · xH₂O
• CAS Number: 207737-97-1
• Molecular Weight: 521.69 (anhydrous basis)
• Beilstein/REAXYS Number: 3901204
• MDL number: MFCD00149238
• UNSPSC Code: 12161900
• PubChem Substance ID: 24899897
• NACRES: NA.25

Properties

• description: anionic
• product line: BioXtra
• assay: ≥97% (TLC)
• mol wt: micellar avg mol wt 3100
• aggregation number: 6
• impurities: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 1-4 mM (20-25°C)
• solubility: H₂O: 0.5 M, clear, colorless to faintly yellow
• anion traces: chloride (Cl^-): ≤0.5%; sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%; Ca: ≤0.005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.01%; Mg: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1
• InChI key: OLPIZAYYAVQETM-GGPRKOIFSA-M

Description

General description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

application

Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)