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Key Documents

L9026

Sigma-Aldrich

Lys-Lys-Lys-Lys

≥95% (TLC)

Synonym(s):

Lys4, Tetralysine

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About This Item

Empirical Formula (Hill Notation):
C24H50N8O5
CAS Number:
Molecular Weight:
530.70
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Lys-Lys-Lys-Lys, ≥95% (TLC)

Quality Level

assay

≥95% (TLC)

form

powder or crystals

composition

Peptide content, ≥50%

color

white

storage temp.

−20°C

SMILES string

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C24H50N8O5/c25-13-5-1-9-17(29)21(33)30-18(10-2-6-14-26)22(34)31-19(11-3-7-15-27)23(35)32-20(24(36)37)12-4-8-16-28/h17-20H,1-16,25-29H2,(H,30,33)(H,31,34)(H,32,35)(H,36,37)

InChI key

RRBGTUQJDFBWNN-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys-Lys

Biochem/physiol Actions

Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adele Aronica et al.
Biochimica et biophysica acta, 1861(1 Pt A), 3210-3220 (2016-08-19)
CA19.9 antigen has been assumed as an abundant product of cancer cells, due to the reactivity found by immunohistochemical staining of cancer tissues with anti-CA19.9 antibody. Expression and biosynthesis of type 1 chain Lewis antigens in the colon and the
Donghong Zhang et al.
Nature communications, 8(1), 1979-1979 (2017-12-08)
Despite the importance of cardiomyocyte proliferation in cardiac development and regeneration, the mechanisms that promote cardiomyocyte cell cycle remain incompletely understood. RE1 silencing transcription factor (REST) is a transcriptional repressor of neuronal genes. Here we show that REST also regulates
Anne L Jaquiery et al.
Pediatric research, 80(6), 861-869 (2016-08-17)
The nutritional plane and composition during fetal life can impact upon growth and epigenetic regulation of genes affecting pancreatic β-cell development and function. However, it is not clear whether β-cell development can be altered by nutritional factors or growth rate
Maja Semanjski et al.
Science signaling, 11(547) (2018-09-13)
The bacterial serine-threonine protein kinase HipA promotes multidrug tolerance by phosphorylating the glutamate-tRNA ligase (GltX), leading to a halt in translation, inhibition of growth, and induction of a physiologically dormant state (persistence). The HipA variant HipA7 substantially increases persistence despite
Tohru Fujiwara et al.
Biochemical and biophysical research communications, 485(2), 380-387 (2017-02-22)
The transcription factor GATA-1-interacting protein Friend of GATA-1 (FOG1) is essential for proper transcriptional activation and repression of GATA-1 target genes; yet, the mechanisms by which FOG1 exerts its activating and repressing functions remain unknown. Forced FOG1 expression in human

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