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H1377

Sigma-Aldrich

4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt

Synonym(s):

3-Methoxy-4-hydroxy-phenylglycol piperazine, MHPG piperazine, MOPEG, MOPEG piperazine

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About This Item

Empirical Formula (Hill Notation):
C9H12O4 · 0.5C4H10N2
CAS Number:
67423-45-4
Molecular Weight:
227.26
Beilstein/REAXYS Number:
7360817
EC Number:
266-689-7
MDL number:
MFCD00065957
UNSPSC Code:
12352200
PubChem Substance ID:
24277759
NACRES:
NA.77

storage temp.

2-8°C

SMILES string

C1CNCCN1.COc2cc(ccc2O)C(O)CO.COc3cc(ccc3O)C(O)CO

InChI

1S/2C9H12O4.C4H10N2/c2*1-13-9-4-6(8(12)5-10)2-3-7(9)11;1-2-6-4-3-5-1/h2*2-4,8,10-12H,5H2,1H3;5-6H,1-4H2

InChI key

KCECBJRHWSOTMR-UHFFFAOYSA-N

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Biochem/physiol Actions

Cerebral norepinephrine metabolite.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M L Laorden et al.
Life sciences, 66(9), 803-815 (2000-03-04)
Previous report from our laboratory showed that morphine produces a stimulatory effect of hypothalamic noradrenaline (NA) turnover concurrently with enhanced pituitary-adrenal response after its acute injection and during withdrawal. In the present work we have studied the effects of acute
J M Duine et al.
Journal of chromatography. B, Biomedical sciences and applications, 716(1-2), 350-353 (1998-11-21)
A reversed-phase chromatographic method with electrochemical detection was developed for the simultaneous determination of 2,3- and 2,5-dihydroxybenzoates, indicators of in vivo hydroxyl free radical formation, monoamines (NE, DA, 5-HT) and their metabolites (MHPG, DOPAC, HVA, 3MT, 5-HIAA). Linearity was observed
Y Wada et al.
Japanese journal of pharmacology, 78(2), 237-240 (1998-11-26)
To study the circadian rhythm of the monoamine and metabolite contents, cerebrospinal fluid was taken from the cisterna magna through a polyethylene catheter tube every 4 hr in the conscious rat. Norepinephrine and 3-methoxy-4-hydroxy-phenylglycol were found to describe a rhythm

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