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S0100000

Salbutamol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol, Albuterol

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About This Item

Empirical Formula (Hill Notation):
C13H21NO3
CAS Number:
18559-94-9
Molecular Weight:
239.31
Beilstein/REAXYS Number:
6405698
MDL number:
MFCD00148978
UNSPSC Code:
41116107
PubChem Substance ID:
329824412
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

albuterol, salbutamol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(C)NCC(O)c1ccc(O)c(CO)c1

InChI

1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

InChI key

NDAUXUAQIAJITI-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salbutamol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

β2-adrenoceptor agonist

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Salbutamol impurity B, British Pharmacopoeia (BP) Reference Standard

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

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M Reza Maleki-Yazdi et al.
Respiratory medicine, 108(12), 1752-1760 (2014-12-03)
Combinations of inhaled long-acting bronchodilator therapies such as muscarinic antagonists and β2-agonists may be more effective than monotherapy in the treatment of chronic obstructive pulmonary disease (COPD). This study was a 24-week, Phase III, multicenter, randomized, blinded, double-dummy, parallel-group study
Karim Makhlouf et al.
CNS drugs, 16(1), 1-8 (2002-01-05)
The beta2-adrenergic receptor agonist salbutamol (albuterol) has been used for many years in the treatment of bronchospasm in patients with asthma. In this patient group, salbutamol is a relatively safe and inexpensive drug, and is easy to administer. Within the
Jean-Louis Pepin et al.
Chest, 146(6), 1521-1530 (2014-07-25)
Increased arterial stiffness as measured by aortic pulse wave velocity (aPWV) predicts cardiovascular events and mortality and is elevated in patients with COPD. Prior investigation suggests that a long-acting β-agonist (LABA)/inhaled corticosteroid (ICS) lowers aPWV in patients with baseline aPWV
L Gnatiuc et al.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 19(1), 21-30 (2014-12-19)
Increasing access to essential respiratory medicines and influenza vaccination has been a priority for over three decades. Their use remains low in low- and middle-income countries (LMICs), where little is known about factors influencing use, or about the use of
Thomas Ritz et al.
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Hyperventilation has been associated with adverse effects on lung function, symptoms, and well-being in asthma. We examined whether raising end-tidal CO2 levels (ie, Pco2) compared with slow breathing is associated with improvements in asthma control, including peak flow variability. One
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