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E9876

Supelco

Ethylhydrocupreine hydrochloride

analytical standard

Synonym(s):

Optochin

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About This Item

Empirical Formula (Hill Notation):
C21H28N2O2 · HCl
CAS Number:
Molecular Weight:
376.92
Beilstein/REAXYS Number:
4055970
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34

InChI

1S/C21H28N2O2.ClH/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19;/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3;1H/t14-,15-,20-,21+;/m0./s1

InChI key

QNRATNLHPGXHMA-XZHTYLCXSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sensitive and specific reagent for the identification of Streptococcus pneumoniae.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Rehab H Bahy et al.
Jundishapur journal of microbiology, 9(4), e30708-e30708 (2016-06-16)
Streptococcus pneumoniae is still one of the major causes of morbidity and mortality worldwide. The prevalent serotype distribution had shown variation along different studies conducted at different time intervals. In order to efficiently assess the epidemiology of the diseases for
Luz Balsalobre et al.
Antimicrobial agents and chemotherapy, 57(1), 254-260 (2012-11-02)
Fourteen fluoroquinolone-resistant streptococcal isolates with recombinant DNA topoisomerase genes, preliminarily identified as pneumococci, were further characterized using phenotypic and genotypic approaches. Phenotypic tests classified them as atypical pneumococci. Phylogenetic relationships were analyzed by using the sequences of seven housekeeping alleles
C William Wester et al.
Diagnostic microbiology and infectious disease, 42(4), 263-268 (2002-05-15)
Standard identification of Streptococcus pneumoniae by optochin and bile solubility testing can lead to ambiguous results for certain isolates. Newer bacteriologic identification techniques (e.g., DNA probes) now exist. In a prospective point prevalence study of oropharyngeal S. pneumoniae carriage rates
Paulo R Cortes et al.
The Journal of antimicrobial chemotherapy, 62(5), 973-977 (2008-08-08)
The aim of this work was to study the effect of subinhibitory concentrations of penicillin, chloramphenicol and erythromycin on the mutation rate of Streptococcus pneumoniae. The mutation rate to rifampicin and optochin resistance was estimated using fluctuation analysis in three
A Pikis et al.
The Journal of infectious diseases, 184(5), 582-590 (2001-07-28)
Traditionally, Streptococcus pneumoniae is identified in the laboratory by demonstrating susceptibility to optochin. Between 1992 and 1998, 4 pneumococcal isolates exhibiting optochin resistance were recovered from patients at Children's National Medical Center. Three of the 4 isolates consisted of mixed

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