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Key Documents

860417

Sigma-Aldrich

Salicylamide

99%

Synonym(s):

2-Hydroxybenzamide

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About This Item

Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
Beilstein/REAXYS Number:
742439
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

solid

mp

140-144 °C (lit.)

SMILES string

NC(=O)c1ccccc1O

InChI

1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)

InChI key

SKZKKFZAGNVIMN-UHFFFAOYSA-N

Gene Information

human ... AR(367)

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General description

Salicylamide is used as a starting material for synthesizing substituted salicylamides through acylation reactions.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Patricia D Sauzem et al.
European journal of medicinal chemistry, 43(6), 1237-1247 (2007-09-25)
In this work, we reported the synthesis and evaluation of the analgesic and anti-inflammatory properties of novel 3- or 4-substituted 5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-1-carboxyamidepyrazoles (where 3-/4-substituent=H/H, Me/H, Et/H, Pr/H, i-Pr/H, Bu/H, t-Bu/H, Ph/H, 4-Br-Ph/H and H/Me) designed in the exploration of the bioisosteric
Acylation of salicylamide to 5-acetylsalicylamide using ionic liquids as dual catalyst and solvent
Chen, W et al.
Journal of Industrial and Engineering Chemistry, 16(5), 800-804 (2010)
J A Murillo Pulgarín et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 909-914 (2011-05-13)
A new methodology for the simultaneous determination of salicylic acid and salicylamide in biological fluids is proposed. The strong overlapping of the fluorescence spectra of both analytes makes impossible the conventional fluorimetric determination. For that reason, the use of fluorescence
Zenei Taira et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 803-807 (2004-03-30)
To elucidate the effects of Sho-saiko-to extract and its components, baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, against the effects of longer periods of acute hepatic injury induced by CCl4, we measured serum ALT activity in male Wistar rats for five
José L Castro et al.
Langmuir : the ACS journal of surfaces and colloids, 28(24), 8926-8932 (2012-01-25)
The surface-enhanced raman scattering (SERS) of benzoic acid/benzamide and salicylic acid/salicylamide on silver colloids show important wavenumber shifts with respect to the Raman spectrum of the band assigned to mode 1;ν(ring) when adsorbed on the metal surface (ca. +50 cm(-1)).

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