The solubility of this product is not determined. For analytical purposes, the material is heated to form a liquid and is tested in the neat form. Various sources indicate that this compound is soluble in DMSO, DMF, and Ethanol. Please see the link below to review a publication that indicates stock solutions may then be further diluted in phosphate buffer:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270770/
274666
Thymoquinone
≥98%
Synonym(s):
2-Isopropyl-5-methyl-1,4-benzoquinone
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1 G
$65.50
5 G
$193.39
About This Item
Empirical Formula (Hill Notation):
C10H12O2
CAS Number:
Molecular Weight:
164.20
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
Recommended Products
Quality Level
assay
≥98%
form
solid
technique(s)
titration: suitable
color
yellow
bp
230-232 °C (lit.)
mp
45-47 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
CC(C)C1=CC(=O)C(C)=CC1=O
InChI
1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3
InChI key
KEQHJBNSCLWCAE-UHFFFAOYSA-N
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General description
Thymoquinone (TQ), also known as 2-isopropyl-5-methyl-1, 4-benzoquinone, is present in a crystalline triclinic form. It is the bioactive constituent of the volatile oil of black seed. TQ exhibits anti-inflammatory, antioxidant and anti-neoplastic effects both in vitro and in vivo.[1]
Application
Thymoquinone has been used as an inhibitor of Escherichia coli ATP synthase and cell growth. It is also used as a drug against lower limb ischemia-reperfusion injury of the sciatic nerve and femoral muscle.[2]
Thymoquinone is employed in preclinical studies as a neuroprotective and anticonvulsant agent.
[2]
Thymoquinone is employed in preclinical studies as a neuroprotective and anticonvulsant agent.
[2]
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
219.2 °F - closed cup
flash_point_c
104 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Customers Also Viewed
Chern Chiuh Woo et al.
Biochemical pharmacology, 83(4), 443-451 (2011-10-19)
Thymoquinone is an active ingredient isolated from Nigella sativa and has been investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro and in vivo models since its first extraction in 1960s. Its anti-oxidant/anti-inflammatory effect has been reported
Hala Gali-Muhtasib et al.
The international journal of biochemistry & cell biology, 38(8), 1249-1253 (2005-11-30)
There has been growing interest in naturally occurring compounds with anti-cancer potential. Black seed is one of the most extensively studied plants. This annual herb grows in countries bordering the Mediterranean Sea and India. Thymoquinone (TQ) is the bioactive constituent
Sanjar Alam et al.
International journal of nanomedicine, 7, 5705-5718 (2012-11-28)
Chitosan (CS) nanoparticles of thymoquinone (TQ) were prepared by the ionic gelation method and are characterized on the basis of surface morphology, in vitro or ex vivo release, dynamic light scattering, and X-ray diffractometry (XRD) studies. Dynamic laser light scattering
Thymoquinone: A promising anti-cancer drug from natural sources
Gali-Muhtasib H
The International Journal of Biochemistry & Cell Biology, 38, 1249-1253 (2006)
Regine Schneider-Stock et al.
Drug discovery today, 19(1), 18-30 (2013-09-05)
Thymoquinone (TQ), the main active constituent of black seed essential oil, exhibits promising effects against inflammatory diseases and cancer. TQ, modulates signaling pathways that are key to cancer progression, and enhances the anticancer potential of clinical drugs while reducing their
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Hello I've bought 1 gram of Thymoquinone (product number: 274666) and I wanna use this in different concenteration for MTT assay. Could you please tell me that in which solvent I should dissolve the powder and How can I dillute it with PBS?
1 answer-
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