EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
Synonyms:
EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18
Species:
Human EIF4G1 (1981), Mouse Eif4g1 (208643), Rat Eif4g1 (287986), chicken EIF4G1 (424953), Horse EIF4G1 (100033975), cow EIF4G1 (444858), dog EIF4G1 (100688785), domestic cat EIF4G1 (101085654), Domestic Rabbit EIF4G1 (100009384), domestic guinea pig Eif4g1 (100729118)
UniProtKB ID:
Gene ID:
- Human(1981) Summary: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
- Mouse(208643) eukaryotic translation initiation factor 4, gamma 1
- Rat(287986) eukaryotic translation initiation factor 4 gamma, 1
- chicken(424953) eukaryotic translation initiation factor 4 gamma, 1
- Horse(100033975) eukaryotic translation initiation factor 4 gamma, 1
- cow(444858) eukaryotic translation initiation factor 4 gamma, 1
- dog(100688785) eukaryotic translation initiation factor 4 gamma, 1
- domestic cat(101085654) eukaryotic translation initiation factor 4 gamma, 1
- Domestic Rabbit(100009384) eukaryotic translation initiation factor 4 gamma, 1
- domestic guinea pig(100729118) eukaryotic translation initiation factor 4 gamma, 1
- naked mole-rat(101709881) eukaryotic translation initiation factor 4 gamma, 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-EIF4G antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-EIF4G1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-EIF4G1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Phospho-EIF4G1-S1108 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-p-eIF4G1 (Ser1108) Antibody, clone 4G7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
inhibition assay
western blot
inhibition assay
western blot