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396966

Sigma-Aldrich

Decamethonium bromide

Ion-Pair reagent, ≥99%

Synonym(s):

Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)

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About This Item

Linear Formula:
(CH3)3N(Br)(CH2)10N(Br)(CH3)3
CAS Number:
541-22-0
Molecular Weight:
418.29
Beilstein:
3728288
EC Number:
208-772-2
MDL number:
MFCD00011779
UNSPSC Code:
12352103
PubChem Substance ID:
329755891
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grade

Ion-Pair reagent

Quality Level

100

Assay

≥99%

mp

263-267 °C (lit.)

SMILES string

[Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C

InChI

1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2

InChI key

HLXQFVXURMXRPU-UHFFFAOYSA-L

Gene Information

human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

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Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
19719BQ
00907TZ

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Amina S Woods et al.
Journal of proteome research, 7(8), 3423-3427 (2008-06-27)
We have previously used MALDI mass spectrometry to highlight ammonium- or guanidinium-aromatic interactions via cation-pi bonding and ammonium- or guanidinium-phosphate interactions through salt bridge formation. In the present work, the gas-phase stability and dissociation pathways of the interaction between phosphorylated
Roger L Papke et al.
The Journal of pharmacology and experimental therapeutics, 333(2), 501-518 (2010-01-27)
Transgenic mouse models with nicotinic acetylcholine receptor (nAChR) knockouts and knockins have provided important insights into the molecular substrates of addiction and disease. However, most studies of heterologously expressed neuronal nAChR have used clones obtained from other species, usually human
V A Pashynskaya et al.
Rapid communications in mass spectrometry : RCM, 16(18), 1706-1713 (2002-09-11)
Mechanisms of interaction between the antimicrobial drugs decamethoxinum and aethonium, which are based on bisquaternary ammonium compounds, and a phospholipid component of biological membranes, dipalmitoylphosphatidylcholine, were studied by means of liquid secondary ion mass spectrometry (LSIMS) and differential scanning calorimetry
Chigusa Sawamura et al.
Magnetic resonance in medicine, 56(6), 1235-1241 (2006-11-08)
To examine the effect of immobilization on the development of articular cartilage, we assessed glycosaminoglycan (GAG) content in the chick articular surface by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). Chick embryos were paralyzed by decamethonium bromide (DMB) from day 10
Dana B Finley et al.
Journal of pharmacological and toxicological methods, 59(2), 108-119 (2009-04-16)
Exposure to irreversible cholinesterase (ChE)-inhibiting compounds, such as organophosphates may produce neuromuscular dysfunction. However, less is known about changes in neuromuscular transmission after treatment with reversible ChE-inhibitors. These studies adapted single fiber electromyography (SFEMG) techniques to quantify neuromuscular jitter in
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