Skip to Content
Merck
All Photos(3)

Documents

753084

Sigma-Aldrich

Poly(ethylene glycol) diamine

average MN 2,000, cross-linking reagent carboxyl reactive, amine

Synonym(s):

Poly(ethylene glycol) bis(amine), Polyethylene glycol, O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
H2N(CH2CH2O)nCH2CH2NH2
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) diamine, average Mn 2,000

form

powder

Quality Level

mol wt

Mw/Mn ≤1.4
average Mn 2,000

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Poly(ethylene glycol) diamine (PEGD) is a non-toxic biopolymer which has properties such as biocompatibility and biodegradability. It can be reacted with crosslinking agents to form a three dimensional mesh that can be used in drug delivery systems. It can also be used as a non-ionic surfactant for a variety of biological applications.

Application

PEGD can be used as a crosslinked hydrogel and as a substrate in tissue engineering and biomedical applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering
Elbert DL and Hubbell JA
Biomacromolecules, 2(2), 430-441 (2001)
Glass surfaces grafted with high-density poly (ethylene glycol) as substrates for DNA oligonucleotide microarrays
Schlapak R, et al.
Langmuir, 22(1), 277-285 (2006)
Rigidity of two-component hydrogels prepared from alginate and poly (ethylene glycol)- diamines
Eiselt P, et al.
Macromolecules, 32(17), 5561-5566 (1999)
Thermal and kinetic evaluation of biodegradable thermo-sensitive gelatin/poly (ethylene glycol) diamine crosslinked citric acid hydrogels for controlled release of tramadol
Rocha-Garcia D, et al.
European Polymer Journal, 89, 42-56 (2017)
K Kawasaki et al.
Chemical & pharmaceutical bulletin, 43(12), 2133-2138 (1995-12-01)
Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000.

Articles

Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service