A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.

A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.

Organic letters (2009-02-26)

Jiarong Li, Xian Chen, Daxin Shi, Shuling Ma, Qing Li, Qi Zhang, Jianhong Tang

PMID19239261

摘要

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5-10 mol %) at 190-200 degrees C in the sealed reactor.

材料

產品編號

品牌

產品描述

186317

Sigma-Aldrich

N,N-二乙基甲酰胺, 99%