The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes.

The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes.

Journal of biomedicine & biotechnology (2012-11-03)

Joanne S J Chia, Jennifer L McRae, Peter J Cowan, Karen M Dwyer

摘要

Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73.

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A6410

Sigma-Aldrich

三磷酸腺苷双磷酸酶来源于马铃薯, ATPase ≥200 units/mg protein, lyophilized powder

A6535

Sigma-Aldrich

三磷酸腺苷双磷酸酶来源于马铃薯, ATPase ≥200 units/mg protein, lyophilized powder

A6132

Sigma-Aldrich

三磷酸腺苷双磷酸酶来源于马铃薯, ATPase ≥3.0 units/mg protein, lyophilized powder

A7646

Sigma-Aldrich

三磷酸腺苷双磷酸酶来源于马铃薯, ATPase ≥60 units/mg protein, lyophilized powder (partially purified)

A2230

Sigma-Aldrich

三磷酸腺苷双磷酸酶来源于马铃薯, High Activity, ATPase ≥600 units/mg protein, lyophilized powder