G005175

SFC Analysis of Chlorpheniramine Enantiomers on Astec^® Cellulose DMP, Methanol Gradient

application for SFC

屬性

• 測試參數: column: Astec Cellulose DMP, 15 cm x 4.6 mm I.D., 5 μm particles (51098AST); gradient: Gradient of 5-65% methanol in 3 min, hold for 1 min; mobile phase: [A] CO₂; [B] methanol;; flow rate: 4 mL/min; pressure: 1450 psi (100 bar); column temp.: 35 °C; detector: UV, 220 nm; injection: 5 μL; sample: chlorpheniramine, 2 mg/mL
• 適合性: application for SFC
• 應用: pharmaceutical (small molecule)

描述

分析報告

SFC data provided by Dr. Christina Kraml, Lotus Separations, LLC, Princeton, NJ.
Instrument: Berger Analytical SFC system equipped with a dual pump (FCM-1200), autosampler (ALS 3100), column oven (TCM-200) and diode-array detector (DAD-4100); from Mettler Toledo.

法律資訊

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

分析物

(±)-Chlorpheniramine maleate salt, ≥99% (perchloric acid titration)