化驗
≥97% (HPLC)
形狀
powder
技術
cell culture | mammalian: suitable
儲存溫度
−20°C
SMILES 字串
CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(O)=O
InChI
1S/C30H44N8O10S2/c1-3-14(2)24-29(46)34-18(8-9-22(32)40)26(43)36-20(11-23(33)41)27(44)37-21(30(47)48)13-50-49-12-17(31)25(42)35-19(28(45)38-24)10-15-4-6-16(39)7-5-15/h4-7,14,17-21,24,39H,3,8-13,31H2,1-2H3,(H2,32,40)(H2,33,41)(H,34,46)(H,35,42)(H,36,43)(H,37,44)(H,38,45)(H,47,48)
InChI 密鑰
ITRWUGOBSKHPTA-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
Amino Acid Sequence
Cys-Tyr-Ile-Gln-Asn-Cys [Disulfide bridge: 1-6]
應用
Tocinoic acid is an oxytocin receptor antagonist and is used to study effects of oxytocin and 5-HT1A receptors on the prosocial effects of 3,4 methylenedioxymethamphetamine (MDMA; ecstasy). It can also be used as a test compound for studying whether the release of protein disulfide isomerase activity is stimulated by activated platelets or not.
生化／生理作用
Tocinoic acid contains the ring structure of oxytocin that inhibits the release of melanocyte-stimulating hormones (MSH) the rat pituitary in vitro.
其他說明
N-terminal hexapeptide fragment of oxytocin.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
A P Da Costa et al.
Journal of neuroendocrinology, 8(3), 163-177 (1996-03-01)
Oxytocin (OT) release within the brain is thought to play a major role in inducing maternal behaviour in a number of mammalian species but little is known about the sites of release which are important in this respect. We have
A V Sirotkin et al.
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 68(1), 112-115 (1982-01-01)
Administration of arginin-vasotocin, oxytocin and their fragments had no effect on corticosterone content in the blood plasma of 10-month chickens whereas in 20 and 30-day chickens arginin-vasotocin and its terminal fragment: amid of prolyl-arginil-glycil, considerably increased the corticosterone content. The
M A Lang et al.
The American journal of physiology, 251(1 Pt 2), R77-R81 (1986-07-01)
To characterize the V2 receptor (for antidiuretic hormone), we have studied the effect of a number of neurohypophysial hormone analogues on cyclic AMP (cAMP) accumulation and short-circuit current in cultured epithelia formed by A6 cells. A6 is the designation of
C Fotsch et al.
Bioorganic & medicinal chemistry letters, 9(15), 2125-2130 (1999-08-28)
On-resin macrocyclization via an SNAr reaction is employed in the synthesis of tocinoic acid analogs. Specifically, an N-terminal nitrofluorobenzene is attacked by a nucleophilic C-terminal sidechain. The remaining nitro group can be reduced and acylated. NMR is used to compare
K Chen et al.
Blood, 79(9), 2226-2228 (1992-05-01)
The release of protein disulfide isomerase by activated platelets was hypothesized on the basis of reported intermolecular and intramolecular thiol-disulfide exchange and disulfide reduction involving released thrombospondin in the supernatant solution of activated platelets (Danishefsky, Alexander, Detwiler: Biochemistry, 23:4984, 1984;
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