推薦產品
生物源
human
重組細胞
expressed in E. coli
籤條
GST tagged
化驗
≥95% (SDS-PAGE)
形狀
lyophilized
分子量
~52 kDa
包裝
pkg of 100 μg
儲存條件
avoid repeated freeze/thaw cycles
技術
activity assay: suitable
顏色
white
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... ANXA5(308)
一般說明
Annexin V is a member of the annexin family of calcium and membrane-binding proteins that have anticoagulatory and anti-inflammatory properties. The encoded protein is 320 amino acid long and is folded into four domains, each having five α-helices, forming a superhelical globular structure. The ANX5 gene is mapped to human chromosome 4q26-q28 and spans a length of 28kb containing 13 exons and 12 introns.
應用
Annexin V has been used to examine phosphorylation activity of ChaK1 (channel-kinase 1).
生化／生理作用
Annexins are a family of water-soluble proteins that bind to membranes and phospholipids in a calcium-dependent manner. They participate in several cellular functions, such as membrane fusion and cytoskeletal interaction. Annexin V is a potent anticoagulant and serves as a voltage-gated calcium channel when bound to membrane in vitro. It is found to inhibit phospholipase A2 and protein kinase C.
外觀
Lyophilized from PBS, pH 7.4.
重構
Reconstitute with 100 μL deionized water.
其他說明
Recombinant human annexin V fused to a GST-tag.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Claire Pluchart et al.
Journal of thrombosis and thrombolysis, 48(2), 195-202 (2019-06-09)
Thromboembolic events are frequent and serious complications of acute lymphoblastic leukaemia treatment. The importance of chemotherapy in the pathogenesis of this increased risk is enhanced by the fact that thrombosis rarely occurs at diagnosis. Our study aims at investigating the
Shruti Sanjay Taparia et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 130-140 (2016-10-25)
Over the last four centuries, cocoa and chocolate have been described as having potential medicinal value. As of today, Theobroma cacao L. (Sterculiaceae) and its products are consumed worldwide. They are of great research interest because of the concentration dependent
Shanyue Wang et al.
International immunopharmacology, 84, 106513-106513 (2020-04-25)
Ischemia-reperfusion (I/R) injury causes cardiac dysfunction through several mechanisms including oxidative stress and pro-inflammation. Eleutheroside E (EE) has protective effects in ischemia tissue and anti-inflammatory action. However, the effect of EE on I/R-injured cardiomyocytes is unknown. In this study, we
Zhiqiang Wei et al.
Chinese medicine, 15, 12-12 (2020-02-07)
Osteoarthritis (OA) is a metabolic disorder and able to be relieved by traditional Chinese medicines. However, the effect of Ligusticum wallichii on OA is unknown. Cytokine IL-1β and L. wallichii extracts were used to stimulate the primary mouse chondrocytes. MTT
Jesse D Gelles et al.
Cell death & disease, 7(12), e2493-e2493 (2016-12-03)
Quantitative and kinetic analyses of apoptotic cell death are integral components of exploring cell biology, measuring cellular stress responses, and performing high-throughput genomic/RNAi/drug screens. Here, we present a detailed method that integrates robust kinetic real-time high-content imaging with Annexin V
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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