SRP6499

HAVCR1/KIM1/TIM1 human

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

• 同義詞: HAVCR, HAVCR-1, Hepatitis A virus cellular receptor 1, TIMD-1, TIMD1
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 生物源: human
• 重組細胞: expressed in HEK 293 cells
• 籤條: 6-His tagged (C-terminus)
• 化驗: ≥90% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: calculated mol wt 31.3 kDa; observed mol wt 80-100 kDa by SDS-PAGE (reducing) (DTT-reduced.)
• 包裝: pkg of 10 and 50 μg
• 雜質: <1 EU/μg endotoxin (LAL test)
• UniProt登錄號: Q96D42
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... HAVCR1(26762)

描述

一般說明

Hepatitis A virus cellular receptor 1 also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.

外觀

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重構

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable