SRP6278

TDRD12-BD2 (908-999) his tag human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 同義詞: ECAT8
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥98% (SDS-PAGE)
• 形狀: liquid
• 分子量: 13 kDa
• 包裝: pkg of 1 mg; pkg of 100 μg; pkg of 20 μg
• 濃度: 2 mg/mL
• UniProt登錄號: Q587J7
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... TDRD12(91646)

描述

一般說明

Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.

外觀

rh-TDRD12-BD2 is supplied as a solution in PBS Buffer containing 10% glycerol.

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable