生物源
human
重組細胞
expressed in E. coli
產品線
PRECISIO®
化驗
≥70% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
比活性
194-290 nmol/min·mg
分子量
~95 kDa
技術
cell culture | mammalian: suitable
NCBI登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... DYRK3(8444)
一般說明
DYRK3 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 is belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. DYRK3 expressed in E. coli undergoes tyrosine autophosphorylation and catalyzes phosphorylation of histones H3 and H2B in vitro. DYRK3 regulate different steps of the caveolar cycle. DYRK3 can promote cell survival through phosphorylation and activation of SIRT1. DYRK3 directly phosphorylate SIRT1 at Thr(522), promoting deacetylation of p53.
外觀
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
準備報告
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
法律資訊
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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