SRP0700

STAT5B Protein

recombinant

• 分類程式碼代碼: 12352202
• NACRES: NA.77

屬性

• 重組細胞: expressed in baculovirus infected Sf9 cells
• 化驗: 70-90% (SDS-PAGE)
• 形狀: frozen liquid
• 分子量: ~115 kDa
• 濃度: 0.2 μg/μL
• 登錄號: BC065227
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... STAT5B(6777)

描述

應用

Useful for Western blot.

生化／生理作用

Recombinant full-length human STAT5B was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. STAT5B or signal transducer and activator of transcription 5B is a member of the STAT family of transcription factors. STATs are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B is activated in response to a variety of cytokines ⁽¹⁾. The JAK/STAT pathway mediates a key signal from the somatic gonad that regulates male germline sexual development ⁽²⁾. STAT5B is critical for maintenance of tolerance in vivo and it is proposed that STAT5B is probably activated by IL2R.

重構

Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

儲存和穩定性

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable