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重要文件

SRP0479

Sigma-Aldrich

GCN5 (727-837) human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

14.1 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... KAT2A(2648)

一般說明

Human GCN5 or KAT2A containing bromodomain (GenBank Accession No. NM_021078) amino-acids 727 – 837 (end) with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Shanshan Li et al.
The Journal of biological chemistry, 284(14), 9411-9417 (2009-02-17)
Bromodomains are acetyl lysine binding modules found in many complexes that regulate gene transcription. In budding yeast, the coactivator complex SAGA (Spt-Ada-Gcn5-acetyl-transferase) predominantly facilitates transcription of stress-activated genes and requires the bromodomain of the Gcn5 subunit for full activation of
Donna A Santillan et al.
Cancer research, 66(20), 10032-10039 (2006-10-19)
A critical unanswered question about mixed lineage leukemia (MLL) is how specific MLL fusion partners control leukemia phenotype. The MLL-cyclic AMP-responsive element binding protein-binding protein (CBP) fusion requires both the CBP bromodomain and histone acetyltransferase (HAT) domain for transformation and

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