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Merck
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Key Documents

SRP0442

Sigma-Aldrich

UEV1A active human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

同義詞:

CIR1, CROC1, UBE2V1, ubiquitin-conjugating enzyme E2 variant 1

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥80% (SDS-PAGE)

形狀

aqueous solution

分子量

20 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... UBE2V1(7335)

一般說明

UEV1A (ubiquitin-conjugating enzyme E2 variant 1), also known as UBE2V1 or CROC-1 (GenBank Accession No. NM_021988) amino acids 2-170 (end) with N-terminal FLAG-tag, MW=20 kDa, expressed in E. coli.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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L Ma et al.
Oncogene, 17(10), 1321-1326 (1998-10-15)
Acquisition of the immortal phenotype by tumor cells represents an essential and potentially rate-limiting step in tumorigenesis. To identify changes in gene expression that are associated with the early stages of cell immortalization, we compared genetically matched pairs of pre-immortal
T M Thomson et al.
FEBS letters, 423(1), 49-52 (1998-05-15)
The open reading frame YGL087c in the budding yeast Saccharomyces cerevisiae genome encodes a polypeptide highly similar to the human UEV (ubiquitin-conjugating E2 enzyme variant) proteins, which have been proposed to belong to a family of putative dominant negative ubiquitin
D Duong Hau et al.
Biochemistry, 45(32), 9866-9877 (2006-08-09)
Lys(63)-linked polyubiquitination of TRAF2 or TRAF6 is an essential step within the signal transduction cascade responsible for activation of p38, c-Jun N-terminal kinase, and the transcription factor NF-kappaB. Attachment of ubiquitin (Ub) to a TRAF, and conjugation of Ub molecules
Jing Geng et al.
Nature immunology, 16(11), 1142-1152 (2015-09-29)
Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample reactive oxygen species (ROS) in phagocytes to kill pathogens. However, how phagosomes transmit signals to recruit mitochondria has remained unclear. Here we found that the kinases Mst1

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