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Key Documents

SRP0418

Sigma-Aldrich

WDR5 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)

同義詞:

BIG-3, SWD3, WD Repeat Domain 5

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

37.5 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... WDR5(11091)

一般說明

Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3 (GenBank Accession No. NM_017588) amino acids 2-334 (end) with N-terminal His-tag, MW=37.5 kDa, expressed in Sf9 insect cells via a Baculovirus expression system.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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WDR5, a complexed protein.
Raymond C Trievel et al.
Nature structural & molecular biology, 16(7), 678-680 (2009-07-07)
Yan-Yi Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(2), 815-820 (2010-01-19)
Viral infection causes activation of the transcription factors NF-kappaB and IRF3, which collaborate to induce type I interferons (IFNs) and cellular antiviral response. The mitochondrial outer membrane protein VISA acts as a critical adapter for assembling a virus-induced complex that
Zain Odho et al.
The Journal of biological chemistry, 285(43), 32967-32976 (2010-08-19)
Histone modification is well established as a fundamental mechanism driving the regulation of transcription, replication, and DNA repair through the control of chromatin structure. Likewise, it is apparent that incorrect targeting of histone modifications contributes to misregulated gene expression and

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