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SRP0362

Sigma-Aldrich

CHK2 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

同義詞:

CDS1, LFS2, RAD53, checkpoint kinase 2

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥70% (SDS-PAGE)

形狀

aqueous solution

分子量

91 kDa

包裝

pkg of 10 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... CHEK2(11200)

一般說明

Human Checkpoint kinase 2 (GenBank Accession No. NM_007194), full length with N-terminal HIS-tag, MW=91kDa, expressed in a Baculovirus infected Sf9 cell expression system.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Travis H Stracker et al.
Cell cycle (Georgetown, Tex.), 7(23), 3618-3621 (2008-11-26)
Central to the DNA damage response (DDR) is the highly conserved Mre11 complex consisting of Mre11, Rad50 and Nbs1. The Mre11 complex acts as a sensor of DNA double-strand breaks (DSBs) and regulates the signal transduction cascades that are triggered
Reinhardt HC and Yaffe MB.
Current Opinion in Cell Biology (2009)
Qi-Qiang Guo et al.
The EMBO journal, 39(10), e103111-e103111 (2020-03-19)
The homeostatic link between oxidative stress and autophagy plays an important role in cellular responses to a wide variety of physiological and pathological conditions. However, the regulatory pathway and outcomes remain incompletely understood. Here, we show that reactive oxygen species

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