生物源
human
重組細胞
expressed in baculovirus infected Sf9 cells
化驗
≥80% (SDS-PAGE)
形狀
aqueous solution
分子量
75 kDa
包裝
pkg of 20 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... KDM2B(84678)
一般說明
Human F-Box Protein 10 (FBXL10, also known as KDM2B, JHDM1B, CXXC2, and Histone-H3 K36 demethylase 1B), (GenBank Accession No. NM_032590), amino acids 1-650 with C-terminal FLAG-tag, MW= 75 kDa, expressed in Sf9 cells via a Baculovirus expression system.
應用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
從最近期的版本中選擇一個：
Neil P Blackledge et al.
Molecular cell, 38(2), 179-190 (2010-04-27)
In higher eukaryotes, up to 70% of genes have high levels of nonmethylated cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units. These features, called CpG islands, were identified over 20 years ago, but there remains little mechanistic evidence
Yuji Tanaka et al.
The EMBO journal, 29(9), 1510-1522 (2010-04-10)
The rate-limiting step in ribosome biogenesis is the transcription of ribosomal RNA, which is controlled by environmental conditions. The JmjC enzyme KDM2A/JHDM1A/FbxL11 demethylates mono- and dimethylated Lys 36 of histone H3, but its function is unclear. Here, we show that
David Frescas et al.
Cell cycle (Georgetown, Tex.), 7(22), 3539-3547 (2008-11-13)
Heterochromatin plays an essential role in the preservation of epigenetic information, the transcriptional repression of repetitive DNA elements and inactive genes, and the proper segregation of chromosomes during mitosis. Here we identify KDM2A, a JmjC-domain containing histone demethylase, as a
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