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Merck
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重要文件

SML3501

Sigma-Aldrich

Dehydrocorydaline

≥98% (HPLC)

同義詞:

13-Methylpalmatine, 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium

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About This Item

經驗公式(希爾表示法):
C22H24NO4
CAS號碼:
分子量::
366.43
MDL號碼:
分類程式碼代碼:
41115709
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

-10 to -25°C

SMILES 字串

CC1=C2[N+](CCC3=C2C=C(OC)C(OC)=C3)=CC4=C(OC)C(OC)=CC=C41

InChI

1S/C22H24NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-12H,8-9H2,1-5H3/q+1

InChI 密鑰

RFKQJTRWODZPHF-UHFFFAOYSA-N

生化/生理作用

Alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects
Dehydrocorydaline is an alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects. Dehydrocorydaline attenuates bone cancer pain through suppression M1 phenotype and upregulation M2 phenotype of microglia in the spinal cord.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype.
Huo W, Zhang Y, Liu Y, Lei Y, Sun R, Zhang W, Huang Y, Mao Y, Wang C, Ma Z, Gu X.
Molecular Pain (2018)
Zhi-Yu Yin et al.
Scientific reports, 6, 27129-27129 (2016-06-09)
Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis. Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects and that it can protect the cardiovascular system. However, there are few studies of the antinociceptive effects of DHC

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