推薦產品
品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 3 mg/mL, clear (warmed)
儲存溫度
2-8°C
SMILES 字串
C1(C2=CC=NC=C2)=NN=C(SC3=NC=NC4=C3SC5=C4C=CC=N5)N1CC6=CC=CC=C6
應用
TH1020已用于抑制猪肠单层上皮细胞和小鼠中的toll样受体5(TLR5)。
生化／生理作用
TH1020介导肿瘤坏死因子-α(TNF-α)相关信号传导的抑制，它通过结合TLR5二聚体之间的分子界面以破坏四聚体复合物的形成。
TH1020是一种无细胞毒性的无细胞毒性toll样受体5（TLR5）/鞭毛蛋白复合物抑制剂。TH1020可选择地阻止鞭毛蛋白诱导的TLR5信号转导，而不影响配体诱导的TLR2、TLR3、TLR4、TLR7或TLR8的激活。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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